Daftar Penyakit Yang Dapat Diterapi Dengan Sel Punca Dan Aplikasi Potensial Lainnya

KANKER DARAH

LEUKAEMIA

  • Acute Biphenotypic Leukaemia*
  • Acute Lymphoblastic Leukaemia*
  • Acute Myelogenous Leukaemia*
  • Acute Undifferentiated Leukaemia*
  • Chronic Myelogenous Leukaemia*
  • Chronic Lymphocytic Leukaemia*
  • Juvenile Myelomonocytic Leukaemia*
  • Juvenile Chronic Myelogenous
  • Leukemia (JCML)

MYELOPROLIFERATIVE NEOPLASMS

  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia
  • Essential Thrombocythemia
  • Polycythemia Vera
  • Systemic Mastocytosis*

MYELODYSPLASTIC SYNDROMES

  • Refractory Anemia*
  • Refractory Anemia with Excess Blasts*
  • Refractory Anemia with Excess Blasts in Transformation*
  • Refractory Anemia with Ringed Sideroblasts (Sideroblastic anemia)*
  • Chronic Myelomonocytic Leukaemia*

OTHER BLOOD CANCERS

  • Multiple Myeloma
  • Plasma Cell Leukaemia
  • Waldenstrom's Macroglobulinemia
  • Histiocytic Neoplasms

TUMOR SOLID

  • Hodgkin's Lymphoma*
  • Langerhans’ Cell Histiocytosis*
  • Neuroblastoma*
  • Non-Hodgkin's Lymphoma (Burkitt's Lymphoma)*
  • Retinoblastoma
  • Medulloblastoma
  • Wilms Tumor


KELAINAN DARAH YANG BUKAN KEGANASAN

ANAEMIAS

  • Aplastic Anaemia*
  • Congenital Dyserythropoietic Anaemia
  • Fanconi Anaemia*
  • Paroxysmal Nocturnal Hemoglobinuria

HEREDITARY BONE MARROW FAILURE SYNDROMES

  • Diamond-Blackfan Syndrome*
  • Dyskeratosis Congenita*
  • Pearson's Syndrome
  • Shwachman-Diamond Syndrome*

INHERITED RED CELL ABNORMALITIES

  • Pure Red Cell Aplasia
  • Sickle Cell Anaemia*
  • Beta Thalassemia Major/Cooley's Anaemia*

INHERITED PLATELET ABNORMALITIES

  • Congenital Amegakaryocytosis Thrombocytopenia
  • Glanzmann Thrombasthenia*


KELAINAN IMUN

SEVERE COMBINED IMMUNE DEFICIENCY (SCID)

  • Bare Lymphocyte Syndrome*
  • Omenn Syndrome*
  • Reticular Dysgenesis
  • Neutrophil Actin Deficiency
  • SCID with Adenosine Deaminase
  • Deficiency (ADA-SCID)*
  • SCID which is X-linked*
  • SCID with absence of T & B Cells*
  • SCID with absence of T Cells,
  • Normal B Cells*

NEUTROPENIAS

  • Kostmann Syndrome (Infantile Genetic Agranulocytosis)*
  • Myelokathexis*

PHAGOCYTE DISORDERS

  • Chediak-Higashi Syndrome*
  • Chronic Granulomatous Disease*

INHERITED DISORDERS OF THE IMMUNE SYSTEM & OTHER ORGANS

  • Cartilage-Hair Hypoplasia
  • Gunther’s Disease (Congenital Erythropoietic Protoporphyria)*

OTHER INHERITED IMMUNE SYSTEM DISORDERS

  • Common Variable Immunodeficiency*
  • DiGeorge Syndrome*
  • Evans Syndrome*
  • Hemophagocytic Lymphohistiocytosis
  • IKK Gamma Deficiency (NEMO Deficiency)*
  • IPEX Syndrome*
  • Leukocyte Adhesion Deficiency*
  • Wiskott-Aldrich Syndrome*
  • X-linked Lymphoproliferative Disease (Duncan’s Syndrome)*
  • X-linked Hyper IgM Syndrome
  • Ataxia-Telangiectasia


KELAINAN METABOLIK

LEUKODYSTROPHY DISORDERS

  • Adrenoleukodystrophy*
  • Krabbe Disease (Globoid Cell Leukodystrophy)*
  • Metachromatic leukodystrophy*
  • Pelizaeus-Merzbacher Disease

LYSOSOMAL STORAGE DISEASES

  • Alpha-Mannosidosis*
  • Gaucher’s Disease
  • Niemann-Pick Disease
  • Sandhoff Disease
  • Wolman Disease*

Mucopolysaccharidosis (MPS) Storage Diseases

  • Hunter Syndrome*
  • Hurler Syndrome*
  • Maroteaux-Lamy Syndrome*
  • Mucolipidosis II (I-cell Disease)*
  • Sanfilippo Syndrome*
  • Morquio Syndrome
  • Scheie Syndrome*
  • Sly Syndrome (beta-glucuronidase deficiency)

OTHER METABOLIC DISORDERS

  • Lesch–Nyhan Syndrome*
  • Osteopetrosis*
  • Hermansky-Pudlak Syndrome


Penelitian Klinis

  • Alzheimer’s Disease*
  • Amyotrophic Lateral Sclerosis
  • Autism*
  • Brain Tumour
  • Cardiomyopathy
  • Cartilage repair
  • Cerebral palsy*
  • Cleft Palate Repair (Alveolar)
  • Compartment Syndrome (Battlefield Trauma)
  • Critical Limb Ischemia
  • Crohn's disease
  • Diabetes Type 1*
  • Epidermolysis Bullosa*
  • Ewing Sarcoma
  • Graft-versus-Host Disease (GvHD)
  • Hearing Loss (acquired sensorineural)*
  • HIV*
  • Huntington’s Disease
  • Hypoplastic Left Heart Syndrome*
  • Hypoxic Ischemic Encephalopathy (HIE)*
  • Ischemic Heart Disease
  • Ischemic Stroke
  • Kidney plus stem cell transplant
  • Liver cirrhosis*
  • Lupus
  • Multiple Sclerosis
  • Myocardial Infarction
  • Open cardiac surgery for congenital heart diseases
  • Ovarian Cancer (Link to clinical trials)
  • Parkinson’s Disease
  • Rhabdomyosarcoma
  • Rheumatoid Arthritis
  • Scleroderma
  • Spinal cord injury*
  • Testicular Tumour
  • Tissue Engineered Vascular Grafts for cardiac defects
  • Traumatic Brain Injury
  • Adrenoleukodystrophy
  • Chronic Granulomatous Disease (X-linked)
  • Fanconi Anemia
  • Metachromatic Leukodystrophy
  • Severe Combined Immunodeficiency X-linked (SCID-X1)
  • Severe Combined Immunodeficiency X-linked (ADA-SCID)
  • Sickle Cell
  • Thalassemia
  • Wiskott-Aldrich Syndrome
  • Bronchopulmonary Dysplasia (BPD)
  • Lysosomal Storage Diseases

Daftar penyakit diatas adalah beberapa penyakit yang telah dapat diterapi dengan (sel punca) darah tali pusat dan dari sumber sel punca haematopoietic lainnya, seperti sumsum tulang dan darah tepi. Bank darah tali pusat tidak menjamin bahwa sel tersebut dapat menyembuhkan atau dapat digunakan pada setiap situasi.
Penggunaan dari darah tali pusat hanya dapat ditentukan oleh dokter yang merawat.

* Diterapi dengan (sel punca) darah tali pusat

Referensi:

DCR 920 QR 8.1-8-11 b

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